"Veroshpiron" regulates water-salt metabolism. The drug removes water from the body, promoting potassium retention. When you take it, magnesium also accumulates in the body. Many women use the drug "Veroshpiron" for weight loss.

Is it worth using the drug for this purpose? First you need to understand the indications for its use.

The drug "Veroshpiron" is prescribed:

• at ;
• heart failure;
• for kidney disease;
• with hypokalemia;
• during preparation for surgery.

This medicine cleanses the body of toxins. This is a mild drug that preserves potassium in the body. Women in pursuit of beauty take unnecessary risks. I must say that the result will certainly please them. In the mirror they will see a thinner figure, and the number on the scale will decrease.

Water retention in the body is one of the causes of excess weight, which creates discomfort and brings suffering. When a person loses weight, excess fluid leaves the cells first of all. Therefore, recently they began to use both herbal and medicinal preparations. The diuretic "Veroshpiron" is also used for weight loss.

What will be next? When taken, the body will be damaged. The weight will easily drop, but the needle on the scale will quickly return back. If you pursue the goal of losing weight by any means and continue to take the medicine "Veroshpiron" for weight loss, you can cause irreparable harm to the body.

Due to the high concentration of potassium in the blood, not only metabolic processes are disrupted, but also heart rhythm - up to cardiac arrest. In case of acute renal failure, it is dangerous to take the drug "Veroshpiron" for weight loss, since hyperkalemia develops in the course of such a disease.

The drug "Veroshpiron" is prescribed for polycostous ovary syndrome. In women with this disease, an increased secretion of luteinizing hormone and a decrease are recorded. This leads to menstrual irregularities and infertility. The drug "Veroshpiron" in gynecology is used in the treatment of this disease if a woman is not planning a pregnancy, since the medicine reduces the formation of androgens. The medication "Veroshpiron" can cause bleeding. It is prescribed along with hormonal medications.

Hirsutism is successfully treated with this drug. Most often, it is taken for six months, strictly following the doctor’s instructions. Body hair growth decreases in 70-80% of women, but only after 6 months. It is contraindicated for pregnant women!

When long-term use of the drug "Veroshpiron" is prescribed, the price, as a rule, is very important. In pharmacies it is sold in tablets and capsules, its minimum cost is 68 rubles. And yet, it is strictly not recommended to take this drug. It can reduce weight only for a short period of time. There are herbal preparations that perfectly remove fluid from the body. Well, physical education, running, swimming and a balanced diet are a much more reasonable solution than dubious and dangerous experiments.

There is an opinion that veroshpiron cleanses the body and promotes weight loss, since it removes excess fluid with various substances harmful to humans. But it is not so. This drug actually has an active diuretic effect. It is prescribed to people with pathological edema of various origins. These tablets also have a potassium-saving property, which is very important, since with large fluid losses there is a risk of deficiency of this element necessary for the body. This is how the drug veroshpiron differs from cheap analogues such as furosemide.

What are veroshpiron tablets for?

In medical reference books, this drug is classified exclusively as a diuretic; veroshpiron is not used for weight loss. Verospiron is used:

• with high blood pressure, removing fluid helps reduce it;
• for nephrosis, to partially replace kidney function;
• for fluid retention, as a symptomatic treatment, provided that there is no deficiency of microelements such as potassium and calcium in the body;
• for some conditions during pregnancy, also to remove excess water.

On various forums you can find many messages about how someone got rid of one or two kilograms using veroshpiron tablets. But the effect consists solely in removing fluid from the body, which, by the way, it quickly returns. Therefore, there is a result, but it lasts for a very short period. “Returning” weight provokes panic, and systematic pill-eating begins. Moreover, often in tandem with various stimulants, for example, caffeine.

How to take veroshpiron and is it dangerous?

Only the doctor should decide how long veroshpiron can be taken, weighing the severity of the condition and the possible consequences for the body. Only frivolous young ladies can prescribe these pills on their own, trying to quickly lose weight for some event, who, by the way, are often misled by the inscription on the package “does not remove potassium.” Potassium is very important for the body: it is necessary for the normal functioning of the heart muscle and regulates water-salt balance. Some analogues of veroshpiron produce it in large quantities. But, in addition to potassium, calcium and sodium are also important for the body, and veroshpiron does an excellent job of removing them. If the drug is overdosed, then the pathological lack of water and microelements will be impossible to compensate for with regular drinking; critical dehydration is treated in hospitals with the help of droppers.

When swelling appears, you need, first of all, to think about what caused it, and not about how to quickly get rid of such a cosmetic defect. Edema can be a physiological norm in the following situations:

• after eating salty foods;
• after intense strength training;
• before menstruation.

You can adjust the water balance in the body by avoiding salt and excluding any liquids other than plain water. It will also be useful to diversify your diet with vegetables, especially cucumbers and celery. In the case of intense physical activity, it is not necessary to limit salt intake; you can try to “run out” excess liquid on a treadmill for 30 minutes; there is a high probability that the swelling will quickly subside. In this case, the swelling is short-term in nature; it can go away on its own in 4–5 hours.

Despite the fact that the fat cell contains liquid, its improper removal with the help of veroshpiron and analogues is a real threat not only to health, but also to life. In addition, the fat cell also contains lipids, and only a properly formulated diet will help remove them.

Is it possible to use veroshpiron for weight loss? What effect does this drug have? How and how much does it cost to take such a diuretic? Are there contraindications and side effects when taking veroshpiron tablets? It is these issues that focus the attention of people who decide to use veroshpiron, diuver or other diuretics to combat.

Veroshpiron– a strong diuretic that affects adrenal function. The drug contains a special artificial aldosterone antagonist - spironolactone, which does not retain water in the body, but accelerates the diuretic effect, eliminating excess fluid.

You can speed up the effect of a diuretic by using other diuretics (furosemide, diuver and other analogues)

The main substance is spironolactone. Additional - sodium, magnesium, corn starch and lactose monohydrate. Diuretic tablets contain 25 milligrams of spironolactone, capsules - 50 milligrams and 100 mg of the main substance each.

After using tablets or capsules, spironolactone quickly integrates into the blood, creating a special substance - canrenone. The medicine itself is absorbed by the gastrointestinal tract (GIT) and excreted in urine and feces.

A special feature of the drug is the effect of preserving potassium, which ensures water and electrolyte balance in the body. Also, the diuretic effect is accompanied by a hypotensive effect (lowering blood pressure effect).

Indications for use

• Why and in what cases is a diuretic prescribed? Indications for use of the drug include:
• High blood pressure;
• Hyperaldosteronism (primary and secondary);
• Prevention of hyperaldosteronism;
• Edema of various nature;
• Fluid accumulation (ascites);
• Potassium or magnesium deficiency;

Polycystic ovary syndrome, menstrual irregularities.

A special place is occupied by indications due to liver conditions, such as liver cirrhosis, liver failure and nephrotic syndrome.

Instructions for use One of the diuretics for weight loss is veroshpiron

, instructions for use, which are quite simple. Doctors prescribe a diuretic individually to each person, taking into account the nature of the disease, the patient’s age, concomitant diseases, etc.

The maximum dose of the drug should not be more than 400 milligrams per day.

Veroshpiron can be taken both after meals and before, depending on the doctor’s recommendations, from 1 to 4 times a day, from which the effect of taking the drug occurs on days 3-5.

Only a doctor's prescription will allow you to purchase veroshpiron capsules or tablets.

Dosage

1. Taking the indications as a basis, you can determine what dosage of the diuretic is needed.
2. In the case of primary hyperaldosteronism, the diuretic should be taken 25–100 milligrams four times a day.
3. Treatment of severe hyperaldosteronism - the dosage varies from 50 to 100 milligrams three times a day after meals, with improvement, the dose is reduced to 25 mg per day.
4. In case of potassium or magnesium deficiency, the drug should be taken 25-100 milligrams up to four times a day, provided that other diuretics (diuver, furosemide and other analogues) have not produced the desired effect.
5. In case of diagnosis of primary hyperaldosteronism, the course of treatment is 4 days, and the dosage is prescribed as 100 mg 4 times a day after meals.
6. For preoperative therapy, the diuretic should be taken in the amount of 25-100 milligrams four times a day after meals.
7. Treatment of edema in nephrotic syndrome - the dosage is 25-50 mg four times a day after meals, if other types of exposure have not produced the desired effect.
8. Treatment of edema in heart failure - a diuretic should be taken continuously for five days. The dose ranges from 50 to 100 mg two or three times a day after meals, in combination with drugs such as diuver, furosemide or other analogues. If the effect of use is positive, the dose may be reduced to 25 mg per day.
9. Treatment of edema in liver cirrhosis - the dose is selected individually.

These dosages are suitable for adults, but for children the daily dose of the drug should be less.

Children should be given a diuretic in proportion to their weight at a rate of 1-3.5 milligrams per kilogram. Dose varies 25 to 50 mg up to four times daily. If the required effect is not achieved, the dose should be increased by one level 50-300 mg five days after the start of use.

Contraindications

Diuretic treatment has some contraindications:

• Severe renal failure;
• Age up to 3 years;
• Lactose intolerance;
• Hyperkalemia;
• Hypersensitivity to the components of the drug;
• Hyponatremia;
• Anuria;
• Addison's disease.

There are a number of situations when it is extremely important to know the indications and contraindications: during pregnancy and certain diseases.

During lactation and pregnancy

The action of the diuretic is aimed at the placental barrier, which affects the development of the fetus during pregnancy, and at penetration into breast milk, which changes the composition of the substance. You can use the drug in the second and third trimester of pregnancy to relieve excess swelling, and only under the supervision of a doctor.

If you need to use veroshpiron tablets during lactation, you should stop breastfeeding your child.

With ascites

For ascites as a result of nephrotic syndrome, the medication is contraindicated. For ascites as a result of cirrhosis and liver failure, the drug can be used if other options are ineffective, since the diuretic can complicate the course of the disease. It is necessary to constantly monitor the amount of electrolytes in the blood.

For polycystic disease

The use of veroshpiron for polycystic ovary syndrome directly depends on hormonal levels. In case of an excess of male hormones, use is contraindicated.

Low pressure

It is worth monitoring the hypotensive effect of the drug. With cardiac obstruction, the blood pressure in the body is low, so avoid taking a diuretic. High blood pressure can be stabilized with veroshpiron tablets.

Alcohol and traffic control

Alcohol is strictly prohibited during the treatment period, since ethanol interacts with the components of the drug and interferes with the full functioning of the body. At the initial stage of taking a diuretic, you should avoid driving or other means that require a clear reaction and high concentration.

Side effects

Side effects of the drug:

• Nausea;
• Gastritis;
• Liver dysfunction;
• Lethargy, confusion;
• Hyperuricemia and hypercreatininemia;
• Increased urea concentration;
• Hyperkalemia and hyponatremia,
• Deepening of the voice;
• Decreased potency for men;
• Menstrual cycle disorders in women;
• Hives;
• Hypertrichosis;
• Acute renal failure;
• Muscle spasms and cramps.

A large number of side effects make a diuretic not the most suitable tool for combating excess fat .

Veroshpiron for weight loss, like other diuretics (furosemide, diuver and other analogues), is not very suitable because it gets rid of liquid, not fat, which causes extra pounds to be lost. Losing weight with the help of diuretics is a completely popular recipe for weight loss.

Analogs

The most famous analogues of veroshpiron:

• Furosemide;
• Diuver;
• Diuver-5;
• Trifas;
• Lasix.

Diuretics provide relief from a number of diseases; they are also used for body shaping. Veroshpiron for weight loss - can this drug be used to lose excess weight?

Efficacy of Veroshpiron

Veroshpiron is used for weight loss due to its ability to remove excess fluid from the body. Unlike other drugs of this type, Veroshpiron does not remove potassium and magnesium from the blood and lymph, so it is considered the safest. Weight loss is significant - even short-term use of the drug allows you to lose 3-4 kg of weight. But don’t delude yourself – the kilograms are not melting due to adipose tissue (its reserves remain the same). In this case, we are talking more about visual harmony - getting rid of puffiness, the body acquires clear lines.

Information about the drug

Veroshpiron is prescribed for swelling caused by pathologies of the kidneys and liver, as well as for heart failure. The active ingredient of the drug is Spironolactone. Dosage should be determined individually in the doctor's office. The diuretic effect does not develop immediately, but 2-3 days after the start of treatment and persists for several more days after its completion. When losing weight, it is recommended to use the minimum dosage – from 25 to 100 mg per day. The course of treatment is about 2 weeks.

Contraindications and special instructions

While taking Veroshpiron, you should not drink alcohol - alcohol increases the toxic effect on the liver. The drug can cause problems with the endocrine system (decreased libido, pain in the mammary glands, disruption of the menstrual cycle). Quite often, symptoms such as nausea, weakness, dizziness, confusion, hives, itching, rash and convulsions occur. The course of treatment introduces an imbalance in the water and electrolyte balance. Hyperkalemia may develop.

The drug should not be used for acute and chronic renal failure, anuria, hyponatremia, hyperkalemia. You cannot undergo treatment during pregnancy and breastfeeding. A strict contraindication is individual intolerance.

If you decide to lose weight with Veroshpiron, limit your consumption of foods rich in potassium. This category includes apricots, potatoes, bananas, tomatoes, raisins, etc. Another important point: if you are not in enviable health, but still decide to use the drug, remember the need to monitor the level of electrolytes in the serum. If you miss a dose, do not try to make up for lost time - do not take a double dose under any circumstances. Remember, in the initial stages of taking Veroshpiron, you cannot perform work that requires a quick reaction (driving a car is also excluded).

pharmachologic effect

A potassium-sparing diuretic, it is a competitive aldosterone antagonist. In the distal parts of the renal tubules, the drug inhibits the action of aldosterone, aimed at retaining sodium and water in the body, as well as increasing potassium secretion. Due to the blockade of aldosterone receptors, the urinary excretion of sodium and chlorine ions increases, and the excretion of potassium and hydrogen ions decreases.

The hypotensive effect of the drug is due to the presence of a diuretic effect.

The diuretic effect develops on days 2-5 of treatment and persists for 2-3 days after discontinuation of the drug.

Pharmacokinetics

Suction

When taken orally, it is absorbed from the gastrointestinal tract. Bioavailability is 90%.

Eating increases the absorption and bioavailability of spironolactone.

Distribution

Plasma protein binding - 90%. Spironolactone and its metabolites cross the placenta and are excreted in breast milk.

Metabolism

Rapidly metabolized in the liver. The main metabolites of spironolactone are canrenone and 7-alpha-(thiomethyl)-spironolactone.

Removal

Spironolactone and its metabolites are excreted mainly in the urine and, to a lesser extent, in the feces.

Indications for use of the drug VEROSHPIRON

Primary hyperaldosteronism (to clarify the diagnosis and short-term preoperative treatment, as well as for long-term treatment if surgery is not possible);

Edema syndrome (combined use with other diuretics is advisable) in chronic heart failure (in the absence of effect or intolerance to other types of treatment, as well as if it is necessary to increase the effects of other diuretics), liver cirrhosis (accompanied by edema and/or ascites), nephrotic syndrome ( if treatment of the underlying disease is ineffective, limiting the consumption of table salt and liquid, as well as when using other diuretics);

Essential arterial hypertension (in combination with other antihypertensive drugs; the use of the drug is preferable for hypokalemia);

Hypokalemia (if it is impossible to use other methods of correcting potassium levels, including to prevent hypokalemia during treatment with digitalis preparations).

Dosage regimen

At primary hyperaldosteronism during preparation for surgery Veroshpiron prescribed in a daily dose of 100-400 mg. If for some reason surgical treatment is not performed, long-term use is possible. Veroshpirona at the minimum effective dose (the initial dose of the drug is reduced every 14 days to the lowest dose that has an effect). With long-term use, to reduce the risk of side effects, it is advisable to prescribe Veroshpirona in combination with other diuretics.

At edema syndrome in chronic heart failure, liver cirrhosis, nephrotic syndrome the drug is prescribed adults in the initial daily dose of 100 mg, divided into 2 doses. In the future, depending on clinical effectiveness, the daily dose can be reduced to 25 mg or increased to 200 mg.

If the expected diuretic effect is not observed, it is advisable to prescribe a diuretic acting on the proximal renal tubules. Dose Veroshpirona in this case it is recommended not to change.

For children The daily dose of the drug is 3 mg/kg body weight (in 1 or 2 doses).

At essential arterial hypertension The initial daily dose is 50-100 mg (divided into 2 doses). The duration of treatment is at least 2 weeks (since during this time the maximum hypotensive effect develops). Then an individual dose adjustment of the drug is carried out. Recommended use Veroshpiron in combination with other antihypertensive drugs.

At hypokalemia Veroshpiron used in a daily dose of 25-100 mg, if oral administration of potassium supplements and other methods of replenishing its deficiency are ineffective.

Side effect

From the side of water-electrolyte balance: hyperkalemia, hyponatremia, electrolyte imbalance.

From the endocrine system: with long-term treatment in men - gynecomastia and decreased erection, in women - engorgement of the mammary glands, menstrual irregularities; It is possible to change the timbre of the voice in both men and women.

From the digestive system: rarely - nausea, vomiting, diarrhea, gastritis, stomach and duodenal ulcers, gastritis, gastric bleeding.

From the side of the central nervous system: rarely - ataxia, lethargy, headache.

Dermatological reactions: rarely - maculopapular rash, erythema.

Side effects usually regress after discontinuation of the drug.

Contraindications to the use of the drug VEROSHPIRON

Use for liver dysfunction

Use for renal impairment

It is prohibited to take the drug in case of acute renal failure and severe renal dysfunction (KR<10 мл/мин).

special instructions

Although the drug does not have a direct effect on carbohydrate metabolism, special caution is required when prescribing Veroshpirona with diabetes mellitus (especially complicated by diabetic nephropathy) due to the risk of developing hyperkalemia.

When using Veroshpirona in case of edematous syndrome, it is recommended to use other diuretics simultaneously, limit the intake of table salt and liquid, and, if necessary, maintain bed rest.

Due to the possibility of developing hyperkalemia, hyponatremia, hyperchloremic metabolic acidosis and a transient increase in blood urea nitrogen during the use of the drug, systematic monitoring of serum electrolytes and indicators of renal function is required.

It should be taken into account that against the background of the use Veroshpirona Determination of digoxin, cortisol and adrenaline in plasma and serum is difficult.

During the treatment period Veroshpiron alcohol consumption is prohibited.

According to some literature data in experimental studies in animals that were dosed over a long period of time Veroshpirona . Many times exceeding the maximum permissible dose for humans, the occurrence of cancer and myeloid leukemia was noted. Taking into account these data, it is recommended to avoid excessively prolonged use of the drug.

Impact on the ability to drive vehicles and operate machinery

In the initial period of use of the drug Veroshpiron Driving a car and other activities that require rapid psychomotor reactions are prohibited. In the future, the possibility of engaging in these types of activities is determined individually.

Overdose

Symptoms: nausea, vomiting, drowsiness, confusion, skin rash, diarrhea. Possible disturbance of water-electrolyte balance and dehydration of the body.

Treatment: there is no specific antidote. Symptomatic treatment of dehydration and water-electrolyte imbalance should be carried out by prescribing diuretics that increase potassium excretion, parenteral administration of a glucose solution (dextrose) with insulin. In severe cases, hemodialysis should be performed.

Drug interactions

When used simultaneously Veroshpirona with salicylates there is a decrease in the diuretic effect.

When used simultaneously Veroshpirona with other diuretics there is an increase in diuresis.

When used simultaneously Veroshpirona with antihypertensive drugs, the hypotensive effect may be enhanced.

When used simultaneously Veroshpirona with potassium supplements or potassium-sparing diuretics, the risk of developing hyperkalemia increases.

When used simultaneously Veroshpirona with NSAIDs the risk of developing hyperkalemia increases.

When used simultaneously Veroshpirona with ACE inhibitors and ammonium chloride, the risk of developing acidosis increases.

When used simultaneously Veroshpirona with fludrocortisone there is a paradoxical increase in tubular secretion of potassium.

When used simultaneously Veroshpirona with mitotane the effect of the latter decreases.

When used simultaneously Veroshpiron reduces the effect of indirect anticoagulants (coumarin derivatives).

When used simultaneously Veroshpirona with triptorelin, buserelin, gonadorelin, the effect of the latter is enhanced.

Pharmacokinetic interaction

When used simultaneously with Veroshpiron The half-life of digoxin increases. This can lead to an increase in the concentration of digoxin in the blood, up to toxic levels (if it is necessary to use them together, the dose should be reduced or the interval between doses of digoxin should be increased).

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Veroshpiron - instructions for use, analogues, reviews, price

Description of the drug and composition

A drug Veroshpiron is potassium-sparing diuretic. and has a pronounced and long-lasting diuretic effect. The active ingredient of this medicinal product is spironolactone(one of the hormones of the adrenal cortex). This substance has a long-lasting effect and can prevent the retention of water and sodium in the lower parts of the renal tubules. Veroshpiron does not have a significant effect on blood circulation in the kidneys, helps reduce the acidity of urine and reduces the excretion of potassium from the body.

The diuretic effect of this drug helps lower blood pressure. It begins to appear 2-5 days after starting to take Veroshpiron, and persists for 3 days after its discontinuation. After oral administration, spironolactone is completely absorbed from the digestive tract into the blood and enters the kidneys. providing a diuretic effect. The drug is excreted from the body mainly through urine and partly through feces.

Release forms

Verospiron is produced in Hungary by GEDEON RICHTER in the following dosage forms:

• White (or almost white) tablets with a bevel, flat, round, on one side there is the marking “VEROSPIRON” - 25 mg each, 20 pieces in one blister, in a cardboard package.
• Capsules with a yellow cap and a white body, hard, gelatin, with a granular fine-grained mixture of white color - 50 mg each, 10 pieces in a blister, 3 blisters in a cardboard package.
• Capsules with an orange cap and a yellow body, gelatin, hard, with a granular fine-grained mixture of white color - 100 mg each, 10 pieces in a blister, 3 blisters in a cardboard package.

Instructions for use of Veroshpiron

Indications for use

• Edema syndrome due to heart failure (alone or in combination with other drugs and diuretics);
• essential hypertension (as part of complex therapy);
• for the prevention of hypokalemia while taking other diuretics;
• Conn's syndrome (primary hyperaldosteronism);
• conditions of secondary hyperaldosteronism (ascites and edema in liver cirrhosis, nephrotic syndrome, etc.);
• to perform diagnostic tests for hyperaldosteronism.

Contraindications

• Children under 3 years of age;
• pregnancy period;
• breastfeeding period;
• anuria (impaired urine excretion up to its complete absence);
• lactose intolerance or lactase deficiency;
• galactose and glucose malabsorption syndrome;
• Addison's disease;
• severe forms of renal failure;
• hyponatremia;
• hyperkalemia;
• hypersensitivity to one of the components of the drug.

Veroshpiron is prescribed with caution when:

Side effects

• From the nervous system– lethargy, headaches and dizziness. ataxia, drowsiness, confusion, lethargy.
• From the digestive organs– nausea, diarrhea, constipation. colic and abdominal pain. vomiting, gastritis. intestinal or stomach bleeding. liver dysfunction.
• From the blood side– thrombocytopenia. megablastosis, agranulocytosis.
• From the endocrine organs– in women, menstrual irregularities (dysmenorrhea, metrorrhagia during menopause, amenorrhea), pain in the mammary glands. hirsutism. breast cancer, in men - gynecomastia.
• From the immune system– allergic reactions in the form of drug fever, itching. hives. erythematous and papular rash.
• From the kidneys– acute renal failure.
• From the muscular system– muscle spasms, cramps of the calf muscles.
• From the skin and hair– hypertrichosis (excessive hair growth), baldness.
• Metabolic disorders– increase in blood urea level. creatinine and uric acid. decreased blood sodium levels, hyperchloremic alkalosis or acidosis.

In most cases, after discontinuation of Veroshpiron, side effects gradually disappear.

Treatment with Veroshpiron

How to take Veroshpiron?

Veroshpiron is taken orally in the recommended dosage and washed down with a sufficient amount of water. Tablets or capsules are swallowed whole without chewing. It is advisable to take the drug in the morning or during the day, since taking it before bedtime will disrupt your usual routine.

It is recommended to take Veroshpiron simultaneously with meals or immediately after them. If you miss a dosage, if no more than 4 hours have passed since the prescribed time, you must immediately take the missed dose of the drug. In other cases, you should take the medicine in the usual dosage during your next appointment.

While taking Veroshpiron, it is recommended to avoid consuming excessive amounts of salt and foods rich in potassium (apricots, tomatoes, peaches, dates, oranges, coconuts, grapefruits, bananas, prunes). During treatment with this drug, the consumption of alcoholic beverages is prohibited.

In the initial period of taking Veroshpiron, it is necessary to abandon activities that require speed of psychomotor reactions and increased attention (driving vehicles, working with complex mechanisms, etc.). The duration of such restrictions depends on the individual characteristics of the patient’s health condition.

When prescribing Veroshpiron to elderly people, patients with severe kidney and liver diseases, constant laboratory monitoring of kidney function and the level of electrolytes in the blood serum is recommended. The same monitoring is necessary for patients who are receiving non-steroidal anti-inflammatory drugs while taking this diuretic. If necessary, the doctor can adjust the dose of the drug.

Only a doctor's prescription will allow you to purchase veroshpiron capsules or tablets.

The dosage and duration of taking Veroshpiron is determined only by a doctor, and depends on the diagnosis and severity of the condition:

• Essential hypertension - 50-100 mg once a day, then the dose can be gradually increased to 200 mg (once every 2 weeks), duration of administration is at least 2 weeks.
• Idiopathic hyperaldosteronism – 100-400 mg once a day.
• Severe hyperaldosteronism and hypokalemia – 300-400 mg 2-3 times a day; then, as the condition improves, the dose can be reduced to 25 mg per day.
• Edema in nephrotic syndrome – 100-200 mg per day.
• Edema in heart failure - 100-200 mg 2-3 times a day, for 5 days in combination with thiazide diuretics; then the maintenance dosage can be reduced to 25 mg (determined individually).
• Edema in liver cirrhosis - the dose of Veroshpiron depends on the ratio of Na+/K+ ions in the urine. If this ratio is greater than 1.0, 100 mg is prescribed once a day; if the ratio is less than 1.0, 200-400 mg is recommended once a day; then the maintenance dose is determined individually.
• Diagnostic test for hyperaldosteronism - 400 mg per day, divided into several doses, taken for 4 days. For a long-term test, it may be recommended to take 400 mg per day for 3-4 weeks.
• Preoperative preparation for primary hyperaldosteronism - 100-400 mg per day, divided into 2-3 doses; The duration of treatment is determined individually.

Overdose

An overdose of Veroshpiron is manifested by the following symptoms:

• nausea and vomiting;
• diarrhea;
• skin rash;
• confusion;
• drowsiness;
• dehydration of the body.

If the above symptoms are detected, the patient should rinse the stomach (induce vomiting) and consult a doctor. There is no specific antidote for Veroshpiron. To help the patient, symptomatic therapy is carried out.

Veroshpiron for children

Veroshpiron can be used in pediatric practice as a diuretic for various diseases. The dosage and duration of its use is determined only by the doctor, and the child’s parents must strictly follow all medical recommendations.

Despite the fact that contraindications for this drug indicate a restriction for use by children under 3 years of age, in practice the drug is in some cases prescribed to younger children (including infants). However, treatment with Veroshpiron for children in this age group is carried out in a hospital setting or under strict medical supervision.

Dosage of Veroshpiron for edema in children:

1. The initial daily dose is 1-3 mg/kg for 1-4 doses.

2. After 5 days, the initial dose can be adjusted (if necessary, it can be increased 3 times).

In some cases, especially in infants. after taking Veroshpiron, vomiting occurs. If it appears earlier than half an hour after administration, the child must be given another dose of the drug. If more than half an hour has passed from the time of administration to the attack of vomiting, then there is no need to give another dose.

An overdose of Veroshpiron is especially dangerous in young children. It is accompanied by an increase in many side effects. The child becomes increasingly sleepy. weakness, heart rhythm disturbances or seizures may occur. Signs of dehydration are also detected: lack of saliva, the skin becomes dry, and there may be vomiting or diarrhea. In such cases, it is urgent to stop taking the drug, rinse the child’s stomach and call a doctor or an ambulance.

Use during pregnancy and lactation

Taking Veroshpiron is contraindicated for women during pregnancy and lactation.

If it is necessary to prescribe this drug to nursing mothers, it is recommended to stop breastfeeding. because spironolactone can penetrate into milk and have a negative effect on the child’s body.

Veroshpiron for weight loss

On the Internet and in some media you can find recommendations for taking Veroshpiron for weight loss. Despite the fact that this diuretic drug can get rid of several kilograms by removing fluid from the body, using it for weight loss is strictly prohibited. In addition, the loss of body weight does not occur due to the loss of adipose tissue, and the fluid removed after taking Veroshpiron is easily restored in the coming days.

This diuretic helps remove sodium and calcium ions from the body and causes dehydration. Loss of electrolytes can lead to seizures and cardiac dysfunction, while dehydration can lead to disruption of all body functions. These problems can bring those who want to lose weight this way to the intensive care unit and cause serious health problems in the future.

Also, taking Veroshpiron for the purpose of losing weight may be accompanied by a number of side effects of this drug:

• tendency to bleed;
• liver dysfunction;
• diarrhea, vomiting and nausea;
• menstrual irregularities in women or gynecomastia in men;
• stomach diseases, etc.

We should not forget that uncontrolled use of this diuretic by people with certain kidney diseases can lead to the development of kidney failure and cause the movement of stones through the urinary tract.

Remember! Taking Veroshpiron and other diuretics for the purpose of losing weight is absolutely unjustified and dangerous!

Drug interactions of Veroshpiron

When prescribing Veroshpiron, you should inform your doctor about taking other medications, since this drug can interact with many of them.

Veroshpiron:

• reduces the effectiveness of anticoagulants (coumarin derivatives, Heparin, Indandione);
• reduces the toxicity of cardiac glycosides (Strophanthin K, Digitoxin, Celanide, Korglikon, etc.);
• reduces vascular sensitivity to Norepinephrine;
• reduces the effectiveness of Mitotane;
• enhances the effectiveness of antihypertensive and diuretic drugs;
• enhances the metabolism of Phenazol;
• increases the toxicity of lithium-containing drugs;
• accelerates the excretion of Carbenoxolone, and their combined use leads to sodium retention;
• enhances the effect of Buserelin, Triptorelin and Gonadorelin;
• when taken simultaneously with salicylates, the diuretic effect of the drug decreases;
• when taken with potassium-sparing diuretics or potassium-containing drugs, Indomethacin. aldosterone blockers, angiotensin II antagonists and cyclosporines pose a risk of developing hyperkalemia;
• when taken with cholestyramine and ammonium chloride, the risk of developing acidosis increases;
• when taken with nonsteroidal anti-inflammatory drugs, there is a risk of developing hyperkalemia;
• when taken with Fludrocortisone, increased secretion of potassium in the renal tubules develops; combined use with Digoxin can lead to a slower elimination of the latter and cause its toxic effect on the body.

Analogues of Veroshpiron

Analogs (synonyms) of Veroshpiron, which contain the same active component spironolactone, are:

• Aldactone (UK);
• Vero-Spironolactone (Russia);
• Veroshpilakton (Russia);
• Spirix (Denmark);
• Spironaxane (UK);
• Spironol (Russia);
• Spironolactone (Russia);
• Spironolactone (Unilan) (USA);
• Urakton (Italy).